Thursday, March 24, 2011

Coenzyme Q10 (Q-Gel), Niacin-extended release and Probiotics on renal dialysis

Hi,

 My friend on hemodialysis has tried some dietary supplements and gave feedback to me they have helped in his situations. I am not here to endorse any of these. Just thought to share his observation. ..

  1. After 3-4 months of trying niacin extended -release tablets, (immediate release may not work as it is not tested ) his phosphorus level is now controlled in normal level, and that is also with Renagel.  Before that, even with Renagel, his P is getting way high and skin itching  and other sideeffects show up.

  2. he also noticed some help with Q-gel ( bioavailable formulation of Coenzyme Q10), seems to make his heart stronger by withstanding some sideeffects of dialysis, such as nausea or vomiting. 

  3. For Probiotics, after a few days of trying, he noticed he can excrete faeces more smoothly and that's a big help to him.


   anyway, pls do talk with your healhcare provider before taking in any dietary suppplements. While they may work from soome people, they may trun to be bad for others. Be vigilent about what we take in.

  happy health!

Friday, March 11, 2011

Astaxanthin - potential super antioxidant?

Hi,

    Astaxanthin has showed up in literature as a super antioxidant, 100-500 times the antioxidant capacity of Vitamin E and 10 times the antioxidant capacity of beta-carotene. It is present in some birds and salmon, being highest in sockeye salmon. Some literature data suggests  its beneficial role in combating against acute renal toxicity in HgCls-fed aminal rat. Several clinical trials are ongoing in renal transplant subjects on testing cardiac advantanges., as well as on hemodialysis patients

  There may be some potential of taking astaxanthin to help body through the reduction of cardiac overload, removal of reactive oxygen species (ROS) to attain longer vessel dilation, improvement of  HDL/cholesteral ratio and  modulation of immune system etc.

    Astaxanthin can cross blood-brain barrier and it can populate in CNS and retinal membranes. Its use in eye health has been promising. However, long term safety studies on the use of astaxanthin in human trials is not yet available. Its use in kideny patients is also not reported yet, despites some positive thinking.

----
Ref: 
http://www.biomedcentral.com/content/pdf/1471-2369-9-17.pdf
http://www.ruscom.com/cyan/web02/pdfs/bioastin/batl09.pdf
http://www.cyanotech.com/pdfs/bioastin/axbul62.PDF